Postdoctoral Researcher - Neuroscience, Stem Cells and Genome Editing The Fraunhofer-Gesellschaft () currently operates 76 institutes and research institutions throughout Germany and is the world's leading applied research organization. Around employees work with an annual research budget of 3.0 billion euros. Are you interested in applied biomedical research and drug development? The Fraunhofer Institute for Translational Medicine and Pharmacology ITMP invites you to apply for a versatile postdoc research position in the field of stem cells and genome Editing within Dr. Lukas Cyganek's working group at our site in Göttingen. At our "Translational Neuroinflammation and Automated Microscopy TNM" site in Göttingen, we pursue innovative approaches for the early detection, diagnosis, and treatment of diseases of the central nervous system. Dr. Lukas Cyganek's working group develops innovative human cell and organoid models for drug development and biomarker identification based on induced pluripotent stem cells (iPSCs). As a postdoctoral researcher, your primary focus will be the development of iPSC-based disease models of neurological disorders that can be used in imaging-based high-throughput screenings. You'll develop 2D and organoid models based on human iPSCs to study neurodegenerative diseases and utilize CRISPR/Cas9 for the targeted genetic modification of iPSCs. Furthermore, you'll develop high-throughput screening methods for imaging-based analysis and high-resolution microscopy while optimizing workflows for drug screening and automatization. By applying preclinical compound screening methods, you'll identify novel therapeutics. Additionally, you'll supervise PhD students and interns, ensuring that they are able to fully integrate into our institute culture and work environment. We are looking for an experienced and highly motivated candidate who wants to work at the interdisciplinary interface between medicine, biology, chemistry, and physics. Advanced degree (PhD or equivalent) in biology, pharmacology, biochemistry, or a related field First postdoctoral experience in translational medicine as well as experience in human iPSC culture, CRISPR/Cas technology, and general molecular biology Ability to plan and execute complex experimental approaches Proven expertise through relevant publications in scientific journals Fluency in spoken and written English in - additional German skills are an advantage An integrative personality, equally at home with medical topics and molecular biology, a structured and independent work style, and the ability to work in an international team. The weekly working time is 39 hours. This position is initially limited until 31.12.2025 and also available on a part-time basis. We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, romantic orientation and identity. Severely disabled persons are given preference in the event of equal suitability. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD). With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
